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Medical data is for informational purposes only. You should always consult your family physician, or one of our referral physicians prior to treatment.

Systemic Lupus Erythematosus and

Progressive Systemic Sclerosis

by Anthony di Fabio

The Roger Wyburn-Mason and Jack M. Blount Foundation for the Eradication of

Rheumatoid Disease

AKA The Arthritis Trust of America

7376 Walker Road, Fairview, Tn 37062

Ronald M. Davis, M.D.

Introduction

Lupus Erythematosus and Scleroderma are classified as

vascular diseases, along with polyarteritis nodosa, and some other

diseases, but Lupus and Scleroderma also have one other thing in

common — they can be treated in a similar manner with equally

good results!

Lupus Erythematosus is a chronic, nontuberculous disease of

the skin marked by disklike patches with raised reddish edges and

depressed centers, and covered with scales or crusts. These fall

off, leaving dull-white scars.

Scleroderma is a disease of the skin in which thickened, hard,

ridged, and pigmented patches occur. During the course of the

disease, the connective tissue of the skin layer beneath the

epidermis (corium) and the subcutaneous structures are increased

and a "hidebound" condition results.

The ordinary form of Scleroderma begins in middle life, and

is often considered, by traditional medicine, as incurable.

According to Richard A. Kunin, M.D., "Systemic Lupus

Erythematosus is the classic example of immune system turning

against specific cells in the body in joints. The immune complexes

formed when antigen from cells combines with antibodies from

immune cells, circulate until the spleen and kidney can excrete

them. Along the way these may deposit in various tissues, causing

secondary inflammatory disorders, such as nodules and inflamma-

tion of the skin and kidneys. The spleen is hard-pressed to digest

and excrete all of these complexes and the overload can deposit in

the kidney, causing great damage. In fact, this overload is the most

serious complication of Lupus and a frequent cause of death."

The Case of Suzie White

Suzie White 40 years-of-age, had a 2 to 3 year history of

finger stiffness and pain and swelling (edema) of toes and the

fingers. She also had marked sensitivity to the sun, with mild to

moderate butterfly lesions across her nose and cheeks.

The Houston Medical Center (Texas) diagnosed Suzie's

condition as Systemic Lupus Erythematosus. She was advised by

that center to take gold shots, and the other traditional palliative and

damaging treatments.

Instead, under the care of Ronald M. Davis, M.D.,

Suzie

decided to try intravenous EDTA (ethylene diamine tetracetic)

chelation therapy and DMSO (Dimethylsulfoxide). These infu-

sions also included magnesium sulphate, sodium bicarbonate,

Vitamin C, pyridoxine, B-complex, dexpanthenol, and Vitamin

Oral metronidazole and allopurinol -- following The Arthritis

Trust of America/The Rheumatoid Disease Foundation treatment

protocol as described in "The Roger Wyburn-Mason, M.D., Ph.D.

Treatment for Rheumatoid Disease," http://www.arthritistrust.org.

She was very lax about taking her intravenous infusions and

would come in weekly until she began feeling better, and then she'd

wait 2-10 weeks before coming in again. Despite this laxness,

Suzie did very well and became free of symptoms.

One year and eight months after starting her treatments with

Dr. Davis, Suzie was given 2 hydrogen peroxide intravenous

infusions (0.03%) within 2 hours of one another. She has been free

of symptoms for the past 3 years.

Dr. Davis says, "As you can see, the anti-amoebic regimen is

included in my treatment protocol. I believe this to be most

important in treating these diseases. It is amazing how these

patients respond to "The Roger Wyburn-Mason, M.D., Ph.D.

Treatment for Rheumatoid Disease," http://www.arthritistrust.org.

What is Systemic Lupus Erythematosus?

Systemic Lupus Erythematosus is an inflammatory connec-

tive tissue disorder of unknown cause occurring chiefly in young

women, and also in children and older adults. According to Alan

Gaby, M.D., the word "lupus" is latin for "wolf," and erythemato-

sus means "redness," together the terms represent or refer to the red

lesions appearing on the face and that resemble a wolf's bite.

Historical Identification

Kaposi first recognized skin and visceral involvements in

1872; Osler described skin lesions (polymorphic) in conjunction

with arthritis and kidney failure by the early 1900s. In 1920-30

Systemic Lupus Erythematosus was identified as a distinct disease.

It is now recognized as a disease entity that evolved from a group

of clinical manifestations that include characteristic pathological

and laboratory findings.

Historically there have been two definitions: Cutaneous Sys-

temic Lupus Erythematosus, and Systemic Lupus Erythematosus.

This distinction is no longer felt to reflect two different diseases.

Distribution of Systemic Lupus Erythematosus

There may be as high as 1 per 100,000 among family members

of those afflicted.

The prevalence among African-American, American-Indian

and several Asian groups is higher than among Whites. Black

females have a higher incidence rate of 7 to 8 per 100,000, as

compared to 2 to 3 per 100,000 among White females.

The ratio of female-to-male is approximately 10 to 1, although

this ratio is less likely in childhood when the disease occurs prior

to puberty.

Both pre-puberty and postmenopausal groups reflect a ratio of

2:1 to 3:1.

Clinical Symptoms

Anemia; fever; hair loss; headaches; high blood pressure;

inflammation of lung lining; inflammation of membrane surround-

ing heart; joint pain; kidney problems; sensitivity to light; skin

lesions, including characteristic "butterfly" redness of skin over

cheeks and bridge of nose; symptoms vary according to organ

affected. SystemicLupus Erythematosus manifests itself through

body fluids (humoral) and cellular abonormalities and through

tissue destruction in many different organs.

As this disease progresses, the afflicted may find that it has

been diagnosed differently over time.

It may also be defined as a Mixed Connective Tissue Disease

involving arthralgias or arthritis, swollen hands, inflammation of

muscles (myositis), capillary congestion and swelling (Raynaud's